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My client hit 18% body fat and looked incredible. Then his blood work came back.

HbA1c is elevated in the pre-diabetic range.

The mirror said healthy, but his blood said danger.

This is why I make all clients get blood work. It is possible to have abs and dying organs. You can look fit and be metabolically broken. You can feel fine and be months from diabetes.

In today's newsletter, I want to share with you 8 specific blood tests that will predict your health better than your waistline ever could.

You ready? Let's go 🔥

8 Blood Tests That Will Predict Your Future Better Than Your Waistline

Before getting into these tests, one thing I will mention is that you can get these tests from your local GP. If they can't do this, then I'd recommend a functional blood test.

Functional blood tests help you test for an abundance of markers while giving you instructions on how to improve them.

Companies I recommend are Siphox and Superpower.

Test #1 - Complete Blood Count

Measures your red/white blood cells, platelets, hemoglobin, and hematocrit.

Why it matters:

This test uncovers anemia, infection, immune status, and potential cancer risk, which are all major predictors for long-term health issues and mortality.

This is like checking the fluids in your car. Red blood cells are the gas (carry oxygen), white blood cells are the windshield washer fluid (clear out problems like infections), and platelets are the brake fluid (help stop bleeding).

If any are too low or too high, the whole car runs poorly or breaks down.

Test #2 - Hemoglobin A1C (HBA1C)

Measures your average blood glucose over 2-3 months.

Why it matters:

Higher values reveal prediabetes or diabetes, which are major risk factors for cardiovascular events, kidney dysfunction, and early death, before physical signs are obvious.

Think of this like reviewing your report card from the last semester, but in this case, it's your blood sugar.

You'll see an idea of how you've been performing for months, not just today.

Test #3 - Comprehensive Metabolic Panel (CMP)

Measures liver and kidney function, electrolytes, and blood sugar.

Why it matters:

Seeing imbalances can signal a risk factor for organ failure, diabetes, and adverse heart events, often earlier than any change in weight or waistline.

Think of this like a house inspection that checks the plumbing (kidneys), furnace (liver), wiring (electrolytes), and pantry (blood sugar).

Test #4 - High-Sensitivity C-Reactive Protein (hs-CRP)

This is a measure of your main factor markers of inflammation.

Why it matters:

Even mildly elevated CRP is a strong, independent predictor of future cardiovascular disease, diabetes, and cancer risk.

This is the smoke detector for the body. It doesn't tell you exactly where the fire is, but even a little smoke means something is burning inside.

Test #5 - Apolipoprotein B (APOB)

Measures the total number of atherogenic particles (LDL, VLDL, IDL) in your blood, not just the cholesterol content.

Why it matters:

Each of these particles is capable of contributing to artery plaque build-up, raising heart disease risk.

It's becoming increasingly common to measure your ApoB over your LDL because it gives you a better predictive value in your risk factor.

This is like watching how much snow piles up in your roof’s gutter. One snowflake is harmless, but too many can block water flow and cause damage.

Test #6 - Vitamin D Levels

Measures blood vitamin D concentration.

Why it matters:

Around 75% to even up to 90% of people in the modern world are low on vitamin D. This can lead to weaker bones and immunity, lower energy, and mood dysfunction while increasing your odds of heart disease and certain cancers.

Also, vitamin D is the most anabolic of all nutrients, contributing to your ability to gain muscle and burn fat.

We are solar-powered individuals, and without enough sun, nothing works at full strength.

Test #7 - Functional Hormone Panel (Including Thyroid)

This test measures:

Sex Hormones: Estrogen, progesterone, testosterone, DHEA
​Adrenal Hormones: Cortisol (ideally mapped throughout the day), DHEA-S
​Thyroid Hormones: TSH, free T4, free T3, reverse T3, anti-TPO antibodies
​Pituitary/Hormonal Connectors: LH, FSH, prolactin
​Sleep/Aging: Pregnenolone, melatonin

Why it matters:

Hormone imbalances can drive fatigue, mood changes, poor sleep, metabolism issues, and immune dysfunction years before symptoms are abnormal.

Thyroid function in particular is often missed and can underlie weight changes, mood issues, and future disease risk.

This is like your car's dashboard, which shows the levels of fuel, oil, and other fluids to ensure everything runs smoothly.

Test #8 - Alzheimer’s Blood Test (PrecivityAD2™)

Two proteins in your blood (amyloid beta and p-tau217) give a score called the Amyloid Probability Score (APS2). This score shows how likely it is that you have early signs of Alzheimer’s disease.

Why it matters:

This test can predict Alzheimer's risk up to years before memory loss with a ≥90% accuracy.

This is like checking for rust in your car's engine before it breaks down.

Summary: 8 Blood Markers To Test For Optimal Health

1. Complete Blood Count (CBC)
2. Hemoglobin A1C (HbA1c)
3. Comprehensive Metabolic Panel (CMP)
4. High-Sensitivity C-Reactive Protein (hs-CRP)
5. Apolipoprotein B (APOB)
6. Vitamin D Levels
7. Functional Hormone Panel (Including Thyroid)
8. Alzheimer’s Blood Test (PrecivityAD2™)

If you want to keep your health optimal, I would recommend getting these tests every 6 months to a year.

The Final Word

What you measure is what you manage.

Your body composition shows you how healthy you are on the outside, while blood tests reveal what's happening on the inside.

The great thing about improving these markers is that they not only help you live longer, but they also help you reach your full potential, both physically and mentally.

Your homework now is to get some blood work and to find out how healthy you are.

Onward and upward. 🚀

- Dan

When you're ready, here is 1 way I can help:

1. Promote yourself to 481,539+ subscribers​ by sponsoring this newsletter.

References

1. Seo IH, Lee YJ. Usefulness of Complete Blood Count (CBC) to Assess Cardiovascular and Metabolic Diseases in Clinical Settings: A Comprehensive Literature Review. Biomedicines. 2022 Oct 25;10(11):2697. doi: 10.3390/biomedicines10112697. PMID: 36359216; PMCID: PMC9687310.
2. Arsenault BJ, Boekholdt SM, Kastelein JJP. Lipid parameters for measuring risk of cardiovascular disease. Nat Rev Cardiol. 2011 Apr;8(4):197-206. doi: 10.1038/nrcardio.2010.223. PMID: 21283149
3. Lachin JM, Orchard TJ, Nathan DM; DCCT/EDIC Research Group. Study of the Use of Lipid Panels as a Marker of Insulin Resistance to Predict Cardiovascular Outcomes. Endocr Pract. 2009;15(7):1076-86. PMID: 26517432.
4. Kowall B, Rathmann W, Trapp R, Osterhoff M, Giani G, Petersmann A, et al. Association of glycated hemoglobin A1c levels with cardiovascular outcomes and mortality in individuals without diabetes. Diabetes Obes Metab. 2021 Nov;23(11):2494-2505. doi: 10.1111/dom.14495. PMID: 34781939.
5. Singh S. Does HbA1cc Play a Role in the Development of Cardiovascular Disease? Curr Diabetes Rev. 2018;14(1):69-75. PMID: 30179123.
6. Liang Q, Liu H, Li X, et al. Comprehensive metabolic profiling of Parkinson’s disease by liquid chromatography-high resolution mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2021 Jan 23;1172:122544. doi: 10.1016/j.jchromb.2021.122544. PMID: 33485385.
7. de la Brassinne Bonardeaux O, et al. High-Sensitivity CRP and Occurrence of Cancer in Patients With Cardiovascular Disease. Front Cardiovasc Med. 2025 Feb 12;12:1006754. doi: 10.3389/fcvm.2025.1006754. PMID: 40004724.
8. Lee S, et al. High-Sensitivity C-Reactive Protein and Cancer: Results from the Fourth Korea National Health and Nutrition Examination Survey (KNHANES IV). Korean J Fam Med. 2011 May;32(3):173-81. PMID: 21591473; PMCID: PMC3899404.
9. Wehr E, Pilz S. Does vitamin D deficiency predict tumour malignancy in patients with bone tumours? BMC Cancer. 2020 Oct 21;20(1):1105. doi: 10.1186/s12885-020-07508-9. PMID: 33073335; PMCID: PMC7695905.
10. Kuang Y, Wang L, et al. Vitamin D: Evidence-Based Health Benefits and Recommendations in Clinical Practice. Nutrients. 2025 Jan 14;17(1):188. doi: 10.3390/nu17010188. PMID: 39861407.
11. Broekmans FJ, et al. Hormonal and functional biomarkers in ovarian response. Reprod Biomed Online. 2014 Jun;28(6):687-89. doi: 10.1016/j.rbmo.2014.03.002. PMID: 24366586.
12. Chang MY, et al. Hormonal, functional and genetic biomarkers in controlled ovarian stimulation. Reprod Biol Endocrinol. 2012 Feb 6;10:23. doi: 10.1186/1477-7827-10-23. PMID: 3299595; PMCID: PMC3299595.
13. Gao L, et al. Independent validation of the PrecivityAD2™ blood test to identify brain amyloid pathology: Diagnostic accuracy in an external cohort. Alzheimers Dement. 2025 Apr 7. doi: 10.1002/alz.14044. PMID: 40297425.
14. Meyer PF, et al. Clinical validation of the PrecivityAD2 blood test for identifying brain amyloidosis in symptomatic individuals. JAMA Neurol. 2024 May 21;81(5):420-31. doi: 10.1001/jamneurol.2024.1087. PMID: 38491912.

Disclaimer: This email is provided for educational and informational purposes only and does not constitute providing medical advice or professional services. The information provided should not be used for diagnosing or treating a health problem or disease, and those seeking personal medical advice should consult with a licensed physician.

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